2
Last modified 16 May 2003
4
This folder contains example data files for the HIV-1 env V3 region
5
analyzed in Yang et al. (2000). This is the 10th data set analyzed
6
and the results are in table 12 in that paper. The default
7
specification in the control file codeml.ctl
11
will fit the onw-ratio model (M0), neutral (M0) and selection (M2)
12
models. You can fit more models if you want. Note that the lysin and
13
lysozyme example folders contain files for similar analyses of bigger
16
You run the program by typing
29
Nielsen, R., and Z. Yang. 1998. Likelihood models for detecting
30
positively selected amino acid sites and applications to the HIV-1
31
envelope gene. Genetics 148:929-936.
33
Yang, Z., R. Nielsen, N. Goldman and A.-M. K. Pedersen. 2000.
34
Codon-substitution models for heterogeneous selection pressure at amino
35
acid sites. Genetics 155:431-449.